Highlighted Publications

Mathias RA, Greco TM, Oberstein A,...Cristea IM. (2014) Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity. Cell. 159: 1615-25. Pubmed

Diner BA, Li T, Greco TM, Crow MS, Fuesler JA, Wang J, Cristea IM. (2015) The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. Mol Syst Biol. 11:787. Pubmed

Li T, Chen J, Cristea IM Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated nuclear DNA sensing for immune evasion. Cell Host & Microbe (2013) Nov. 13, Vol. 14, Issue 5, 591-599 | PubMed

Joshi P, Greco TM, Guise AJ, Luo Y, Yu F, Nesvizhskii AI, Cristea IM The functional interactome landscape of the human histone deacetylase family. Molecular Systems Biology (2013) Jun 11;9:672. doi: 10.1038/msb.2013.26 | PubMed

Miteva YV, Budayeva HG, Cristea IM, Proteomics-Based Methods for Discovery, Quantification, and Validation of Protein-Protein Interactions.  Analytical Chemistry (2013) Jan 15;85(2):749-68. doi: 10.1021/ac3033257 | PubMed

Guise AJ, Greco TM, Zhang IY, Yu F, Cristea IM Aurora B-dependent regulation of class IIa histone deacetylases by mitotic nuclear localization signal phosphorylation.  Molecular & Cellular Proteomics (2012) Nov;11(11):1220-9. doi: 10.1074/mcp.M112.021030 | PubMed

Li T, Diner BA, Chen J, Cristea IM.  Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16. Proc Natl Acad Sci U S A. (2012) Jun 26;109(26):10558-63. Epub 2012 Jun 12 | PubMed

Greco TM, Yu F, Guise AJ, Cristea IM.  Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. Molecular & Cellular Proteomics (2011) Feb;10(2):M110.004317. Epub Nov 16 | PubMed