Princeton Biosociology Lab

The Princeton Biosociology Lab seeks to thoughtfully integrate biomarkers and social-behavioral data. Ongoing studies in this vein range from investigating the effect of Neanderthal ancestry on socioeconomic and behavioral outcomes to examining the impact of skin tone on hypertension among African Americans (net of genotype and family background) to developing variance polygenic scores (vPGSs) for phenotypic plasticity (as a prelude to interacting them with exogenous social environments). Other work examines social genetic effects (i.e. effects of random variation in peer genotype on ego's phenotype) in both the school setting and within families (i.e. social niche formation versus synergistic effects). We are also looking at prenatal genetic selection as a threat to sibling fixed effects model estimation (i.e. whether certain genotypes disproportionately survive the antenatal period and the parental correlates of such selection). And we are studying the impact of sibling differences in observable birth endowments (as measured by birth weight) versus initially unobservable birth endowments (genotype as measured by PGSs) in fostering unequal parental investments. Yet other work tests both susceptibility to inattentional blindness and individual differences in the critical flicker fusion rate (CFF -- a measure of visual processing speed) for their association with mental health and cognition in a nationally representative sample.

Currently the lab is funded by the Russell Sage Foundation and the MacArthur Foundation. 

Replication Files, data, GWAS Betas, etc.:

Files for "A Sibling Method for Identifying vQTLs": 

Code to create sibling pairs for FHS

Code for sib-based vGWAS 

vGWAS_FHS_BMI

vGWAS_FHS_Height 

vGWAS_MTFS_BMI

vGWAS_MTFS_Height

Code for simulation