Acute infection induces a metastatic niche: a double menace for cancer patients.

Citation:

Smith, Heath A, and Yibin Kang. “Acute infection induces a metastatic niche: a double menace for cancer patients.”. Clin Cancer Res 19.17 (2013): , 19, 17, 4547-9. Web.

Date Published:

2013 Sep 01

ISSN:

1078-0432

Abstract:

Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics.

DOI:

10.1158/1078-0432.CCR-13-1524

Alternate Journal:

Clin. Cancer Res.