RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression.

Citation:

Esposito, Mark, and Yibin Kang. “RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression.”. Cancer Discov 55 (2015): , 5, 5, 466-8. Web.

Date Published:

2015 May

ISSN:

2159-8290

Abstract:

Considerable evidence points to the importance of disseminated tumor cells, which are commonly detected in the bone marrow and display features of cellular plasticity, in predicting the clinical outcome of breast cancer. In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid-induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor-positive breast cancer.

DOI:

10.1158/2159-8290.CD-15-0352

Alternate Journal:

Cancer Discov