Role Reversal: A Pro-metastatic Function of E-Cadherin

Citation:

Shen, Minhong, and Yibin Kang. “Role Reversal: A Pro-metastatic Function of E-Cadherin”. Dev Cell 51.4 (2019): , 51, 4, 417-419. Web.

Date Published:

2019 11 18

ISSN:

1878-1551

Abstract:

Carcinoma cells often acquire mobility and invasiveness by undergoing epithelial-to-mesenchymal transition, and yet most metastatic lesions remain epithelial in nature. Recently, in Nature, Padmanaban et al. (2019) demonstrated that the quintessential epithelial marker E-cadherin promotes metastasis of invasive ductal breast carcinoma by enhancing the survival of tumor cells.

DOI:

10.1016/j.devcel.2019.10.028

Alternate Journal:

Dev Cell