Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens.

Citation:

von Schaewen, Markus, Gabriela Hrebikova, and Alexander Ploss. “Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens.”. Methods Mol Biol 1438 (2016): , 1438, 79-101. Web.

Date Published:

2016

ISSN:

1940-6029

Abstract:

Human liver chimeric mice have become valuable tools for the study of human hepatotropic pathogens and for the investigation of metabolism and pharmacokinetics of novel drugs. The evolution of the underlying mouse models has been rapid in the past years. The diverse fields of applications of those model systems and their technical challenges will be discussed in this chapter.

DOI:

10.1007/978-1-4939-3661-8_5

Alternate Journal:

Methods Mol. Biol.