Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Citation:

Legrand, Nicolas, et al. “Humanized mice for modeling human infectious disease: challenges, progress, and outlook.”. Cell Host Microbe 61 (2009): , 6, 1, 5-9. Web.

Date Published:

2009 Jul 23

ISSN:

1934-6069

Abstract:

Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.

DOI:

10.1016/j.chom.2009.06.006

Alternate Journal:

Cell Host Microbe