Joshua D. Rabinowitz


Stanford University
M.D., 2001
Ph.D. in Biophysics, 1999

University of North Carolina at Chapel Hill
B.A. with Highest Honors in Mathematics, 1994
B.A. in Chemistry, 1994


Princeton University
Department of Chemistry & Lewis-Sigler Institute for Integrative Genomics
     Professor, 2011–present
     Associate Professor,  2009–2011
     Assistant Professor, 2004–2009
Department of Molecular Biology
     Associated Faculty, 2005–present

Rutgers Cancer Institute of New Jersey, Member, 2008-

Alexza Pharmaceuticals
Co-founder and Vice President, Research, 2000–2004
- Accelerating onset of drug action through thermally generated aerosols


NIH Pioneer Award, 2016

Agilent Thought Leader Award, 2013

Kavli Frontiers of Science Scholar, Kavli Foundation and National Academy of Sciences, 2008

CAREER Award, National Science Foundation, 2007–2013

Beckman Young Investigator Award, Arnold and Mabel Beckman Foundation, 2005–2009

Medical Scientist Training Program (MSTP) Trainee, National Institutes of Health, 1994–2001 

Churchill Fellow (Declined), 1994

Barry M. Goldwater Scholar, Federal Excellence in Education Foundation, U.S. Federal Government, 1993–1994

President, Phi Beta Kappa, University of North Carolina, 1993–1994

Herbert Worth Jackson Scholar, University of North Carolina Honors Program, 1990–1994


See publications tab.


University of California-Sacramento, Comprehensive Cancer Center (2017)
University of California-Davis, West Coast Metabolomics Center (2017)
NYU, Center for Genomics and Systems Biology Symposium (2017)
CSHL, Mechanisms of Metabolic Signaling Meeting (2017)
University of CO, Denver, Dept. of Biochemistry & Molecular Genetics (2017) 
Keystone Symposium on Tumor Metabolism (2017)
CSHL, Chemistry & Metabolism Meeting (2017)
University of California-Los Angeles, David Geffen School of Medicine (2016)
New York Academy of Science (2016)
Rutgers University, Boxer Lecture (2016)
American Association for Cancer Research, New Orleans (2016)
Parker Institute for Cancer Immunotherapy Retreat (2016)
New Frontiers in Understanding Tumor Metabolism/Immunometabolism
   in Immune Function & Inflammatory Disease, Banff, Alberta (2016)
Pfizer, Cardiovascular & Metabolic Disease Research Unit (2015)
Ludwig Cancer Research Center, Inaugural Symposium, Harvard (2015)
US Oncology Network Clinical Science Meeting, Dallas (2015)
Stanford, University, Chemical & Systems Biology Dept. (2015)
American Association for Cancer Research, Philadelphia (2015)
Metabolism, Diet and Disease: Cancer and Metabolism (2014)
American Association for Cancer Research (2014)
Yale University, Department of Chemistry (2013)
University of Pennsylvania, Dept. of Biochemistry & Biophysics (2013)
Cancer Research UK, Cambridge University (2013)
University of Pennsylvania, ITMAT Symposium (2013)
Harvard Medical School, Dept. of Systems Biology (2013)
Duke University School of Medicine, Depts. of Pharmacology & Cancer 
   Biology (2013)
Cancer Institute of New Jersey (2013)
Systems Biology of Infection Symposium, Switzerland (2013)
MIT, Koch Institute for Integrative Cancer Research (2013)
American Society for Microbiology (2013)
American Society for Biochemistry and Molecular Biology Conference (2013)
Keystone Symposium on Tumor Metabolism (2013)
University of Chicago (2012)
United Mitochondrial Disease Foundation (2012)
Memorial Sloan-Kettering Cancer Center (2012)
American Association for Cancer Research, Annual Meeting (2012)
New York Academy of Science (2012)
AFOSR Bioenergy Program Review (2011)
CONO 2011 / Viral Ed Conference (2011)
Rockefeller University (2011)
SU2C Team Meeting (2011)
PhytoMetaSyn Project, Annual Meeting (2011)
Broad Institute (2011)
NJ Governor’s Conference on Effective Partnering in Cancer Research (2011)
Case Western University (2011)
International Conference on Systems Biology, Edinburgh (2010)
Metabolomics Society, Amsterdam (2010)
IEEE International Conference on Bioinformatics & Bioengineering (2010)
American Association for Cancer Research, Washington, DC (Speaker & Session Chair) (2010)
New York Academia of Sciences, Hot Topic Symposium, Learning from the Metabolome (2010)
Department of Energy, Genomic Sciences Meeting (Plenary Speaker) (2010)
Cold Spring Harbor Laboratory (2009)
National Institutes of Health, Cancer Cell Metabolism Workshop (2009)
Dana Farber Cancer Institute, Kidney Cancer Program 
   (Keynote Speaker) (2009)
University of Pennsylvania, Institute for Diabetes,
   Obesity & Metabolism (2009)
University of Tennessee, Department of Chemistry (2009)
Vanderbilt University, Institute of Chemical Biology (2009)
Stanford University, Department of Bioengineering (2008)
University of California-Berkeley, Department of Microbiology (2008)
Harvard University, Medical School, Department of Cell Biology (2008)
University of California-San Diego, Department of Bioengineering (2008)
Institute for Advanced Study, Department of Systems Biology (2008)
University of Pennsylvania, Medical School, Cancer and Diabetes Metabolism
   Seminar (2008) 
Scripps Research Institute, Center for Mass Spectrometry (2008)
Harvard University, FAS Center for Systems Biology (2008)


Inventor of 160 patents issued by U.S. Patent and Trademark Office

Inventor of five drug products in FDA-sanctioned clinical testing.
- The most advanced product treats acute agitation in bipolar and
   schizophrenic patients.  It has successfully completed two phase 3
   clinical trials and will be submitted for FDA approval shortly.
- The other products (several of which are in Phase II trials) treat migraine
   headache, panic attacks, insomnia, and cancer pain.


Principal Investigator, NIH Pioneer, 09/2016-07/2021
Metabolism in Action: Quantitative Fluxes in Mammals

Principal Investigator, SU2C, 12/2015-11/2018
Reprogramming of Transcriptional Circuitry to Control Pancreatic Cancer

Co-Investigator, NIH, 07/2014-06/2018
The Regulation of Cell Metabolism and Proliferation by mTOR Complex 2

Principal Investigator, NIH, 08/2012–06/2022
Identification of Metabolic Vulnerabilities of Ras-Driven Cancer Cells

Principal Investigator, DOE, 09/2014–08/2017
Quantitative Analysis of Metabolic Regulation by Integration of Metabolomics, Proteomics, and Fluxomics

Principal Investigator, Pfizer, 12/2016-05/2020
Targeting Identification/Validation through Quantifying NADPH Flux & Mapping Consumption into de novo lipogenesis (DNL) in Models of NASH/NAFLD


Undergraduate: A Quantitative, Integrative Introduction to the Sciences,
Parts V and VI (with D. Botstein and E. Wieschaus)
A uniquely mathematics-intensive introduction to genetics, physiology, and organic and biological chemistry for college sophomores

Graduate: Biophysical Chemistry I and II
A quantitatively rigorous treatment of biological chemistry for first year science graduate students
Chemical Biology II
A chemically and quantitatively rigorous treatment of metabolism and protein synthesis with a focus on modern advances and techniques

Organic Chemistry of Metabolism
An alternative to the traditional 2-semester sequence in organic chemistry, which teaches the most biologically important reactions through examples drawn from metabolism