Influence of topology on bacterial social interaction.

Citation:

Park, Sungsu, et al. “Influence of topology on bacterial social interaction.”. Proc Natl Acad Sci U S A 100.24 (2003): , 100, 24, 13910-5. Web.

Date Published:

2003 Nov 25

ISSN:

0027-8424

Abstract:

The environmental topology of complex structures is used by Escherichia coli to create traveling waves of high cell density, a prelude to quorum sensing. When cells are grown to a moderate density within a confining microenvironment, these traveling waves of cell density allow the cells to find and collapse into confining topologies, which are unstable to population fluctuations above a critical threshold. This was first observed in mazes designed to mimic complex environments, then more clearly in a simpler geometry consisting of a large open area surrounding a square (250 x 250 microm) with a narrow opening of 10-30 microm. Our results thus show that under nutrient-deprived conditions bacteria search out each other in a collective manner and that the bacteria can dynamically confine themselves to highly enclosed spaces.

DOI:

10.1073/pnas.1935975100

Alternate Journal:

Proc. Natl. Acad. Sci. U.S.A.