Positional Information and Cell Fate Determination in the Early Drosophila Embryo.

Citation:

Wieschaus, Eric. “Positional Information and Cell Fate Determination in the Early Drosophila Embryo.”. Curr Top Dev Biol 117 (2016): , 117, 567-79. Web.

Date Published:

2016

ISSN:

1557-8933

Abstract:

During early development in Drosophila, the spatial information of maternal gradients is translated into discrete transcriptional states determining cell fate. Information transfer depends on reproducibility of the gradients themselves, as well as the ability of cells to accurately measure and utilize morphogen concentrations in biologically meaning ways. In the following essay, these issues are discussed in context of the Bicoid gradient.

DOI:

10.1016/bs.ctdb.2015.11.020

Alternate Journal:

Curr. Top. Dev. Biol.
Last updated on 01/17/2020