Distribution of telomere-associated sequences in yeast.


Zakian, VA, HM Blanton, and L Wetzel. “Distribution of telomere-associated sequences in yeast.”. Basic Life Sci 40 (1986): , 40, 493-8. Print.

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Two middle repetitive DNA sequences called X and Y' are found near the telomeres of many chromosomes in Saccharomyces cerevisiae. Orthogonal field gel electrophoresis (OFAGE) was used to examine the distribution of X and Y' on different yeast chromosomes. Although the distribution of X and Y' varies among different laboratory strains of yeast, most yeast chromosomes in four different strains carry both X and Y'. However, at least one chromosome in each strain lacks the Y' element. This result indicates that Y' is not essential for replication or segregation of at least some yeast chromosomes.

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Basic Life Sci.