Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.

Publication Year
2012

Type

Journal Article
Abstract
The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres--soup to nuts.
Journal
Genetics
Volume
191
Issue
4
Pages
1073-105
Date Published
08/2012
ISSN Number
1943-2631
Alternate Journal
Genetics
PMID
22879408