Telomeric position effect in yeast.


Sandell, LL, and VA Zakian. “Telomeric position effect in yeast.”. Trends Cell Biol 21 (1992): , 2, 1, 10-4. Print.

Date Published:

1992 Jan




Telomeres are the physical ends of chromosomes. In yeast, when a gene is placed near a telomere, its transcription is repressed. Genes under the influence of this telomeric position effects switch between a repressed state and a transcriptionally active state, each of which is stable for many cell generations. Telomeric position effect may provide a model system for the study of heritable gene regulation in other, more complex organisms.

Alternate Journal:

Trends Cell Biol.